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COVID 19 & Pfizer Vaccine

 


COVID 19 & Pfizer Vaccine

Introduction

 At this moment thousands of people are dying per day due to COVID 19. Now it is a global pandemic situation near 1 ½ years since 2019. In 2020 the man is the most intelligent animal in the world. They can fight against any kind of diseases and they already eliminated such kind of dangers diseases from the world. But they could not find any better solution against COVID 19. SARS-CoV2 is the name of the virus which cause to COVID 19. It will be huge threatened for human race.

                                                                    But now scientist found some vaccines in many countries. Now we can get little hope. Initially they tried some drugs but it was not ok.  Vaccine is a biological preparation that provides active acquired immunity to a particular infectious disease. A vaccine typically contains an agent that resembles a disease-causing micro-organism and is often made from weakened or killed forms of microbe, its toxin, or one of its surface proteins. Vaccine is safer and have minor side effects than drugs.

 

National regulatory authorities have approved six vaccines for public use.

2 RNA vaccines

·         Tozinameran from Pfizer-BioNTech

·         m-RNA-1273 from Moderna

 

2 convectional inactivated vaccines

·        BBIBP-CoV from sinopharm

·        CoronaVac from Sinovac

 

2 Viral vector vaccines

·        Gam-Covid-vac from Gamaleya

·        A.ZD1222 from university of Oxford

 

There is Sputnik V vaccine from Russia also.

 

 

                    Pfizer-BNT 166b2 Vaccine

 

Pfizer-BioNtech Vaccine is made by Pfizer and BioNTech companies. This is a mRNA vaccine. It is more than 95% effective in preventing COVID 19 in participants without evidence of prior SARS-CoV-2 infection in the first interim efficacy analysis. So lab test show there are more efficiency to cure COVID 19 by this vaccine.

Number of shots- 2 shots , 21 days apart

 

It given a shot in a muscle in upper arm. There is minor pain while inject the vaccine.

But this vaccine is not approved by FDA even there is no any FDA-approved vaccine to prevent COVID 19. But FDA has authorized the emergency use of the Pfizer-BioNTech COVID 19 vaccine in individuals 16 year of age & older.

 

The people who have saver allergies should not given this Pfizer vaccine.

 

Vaccine includes :-

· Active Ingredient

o    nucleoside-modified messenger RNA (modRNA) encoding the viral spike glycoprotein (S) of SARS-CoV-2

· Lipids

o    (4-hydroxybutyl)azanediyl)bis(hexane-6,1-diyl)bis (ALC-3015)

o    (2- hexyldecanoate),2-[(polyethylene glycol)-2000]-N,N-ditetradecylacetamide (ALC-0159)

o    1,2-distearoyl-snglycero-3-phosphocholine (DPSC)

o    cholesterol

· Salts

o    potassium chloride

o    monobasic potassium phosphate

o    sodium chloride

o    basic sodium phosphate dihydrate 

· Other

o    sucrose

 

 

 

By this vaccine, the duration of protection against COVID 19 is currently unknown.

 

Side effects

·        Injection site pain

·        Tiredness

·        Headache

·        Muscle pain

·        Chills

·        Fever

·        Joint pains

·        Nausea

 

Some times can occur sever allergic within few minutes to 1 hour after getting vaccine for this reason you should inform the provider to stay with you after vaccination to monitor you.

Sometimes it can be caused to sever allergic conditions.

·        Difficulty in breathing

·        Swelling face & throat

·        Increase heart rate

·        Bad rashes

·        Dizziness

 

Glad to say 16 year & older persons can get this vaccine without allergy persons. But there are no any information about pregnant & breast feeding mothers, And no any information on use of Pfizer vaccine with other vaccines.

 

 

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